CLECL1 Human Gene Knockout Kit (CRISPR)

CAT#: KN210857RB

CLECL1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: CLECL1
• Locus ID: 160365
• Components:

  KN210857G1, CLECL1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN210857G2, CLECL1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN210857RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001253748, NM_001253750, NM_001267701, NM_172004
• UniProt ID: Q8IZS7
• Synonyms: DCAL1
• Summary: This gene encodes a type II transmembrane, C-type lectin-like protein that is highly expressed on dendritic and B cells. This protein may act as a T-cell costimulatory molecule that enhances interleukin-4 production, and maybe involved in the regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]