AK2 Human Gene Knockout Kit (CRISPR)

SKU
KN209974BN
AK2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol AK2
Locus ID 204
Components

KN209974G1, AK2 gRNA vector 1 in pCas-Guide CRISPR vector

KN209974G2, AK2 gRNA vector 2 in pCas-Guide CRISPR vector

KN209974BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001199199, NM_001319139, NM_001319140, NM_001319141, NM_001319142, NM_001319143, NM_001625, NM_013411, NM_172199, NR_037591, NR_037592, NR_134976
UniProt ID P54819
Synonyms ADK2; AK 2
Summary Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.provided by RefSeq, Nov 2010
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Other Versions
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GA100141 AK2 CRISPRa kit - CRISPR gene activation of human adenylate kinase 2 1 kit
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KN209974 AK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN209974LP AK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN209974RB AK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409974 AK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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