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YB1 (YBX1) Human Gene Knockout Kit (CRISPR)

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SKU
KN209835LP
YBX1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "YB1 or NM_004559"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol YB1
Locus ID 4904
Components

KN209835G1, YB1 gRNA vector 1 in pCas-Guide CRISPR vector

KN209835G2, YB1 gRNA vector 2 in pCas-Guide CRISPR vector

KN209835LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004559, NR_132737
UniProt ID P67809
Synonyms BP-8; CSDA2; CSDB; DBPB; MDR-NF1; NSEP-1; NSEP1; YB-1; YB1
Summary This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
GA103275 YBX1 CRISPRa kit - CRISPR gene activation of human Y-box binding protein 1 1 kit
$1,657.00
KN209835 YBX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209835BN YBX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209835RB YBX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409835 YBX1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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