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LOXL1 Human Gene Knockout Kit (CRISPR)

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SKU
KN209830LP
LOXL1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA351361 Rabbit Polyclonal Anti-LOXL1 Antibody
100 ul
$205.00
RC209830 LOXL1 (Myc-DDK-tagged)-Human lysyl oxidase-like 1 (LOXL1)
10 ug
$801.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "LOXL1 or NM_005576"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol LOXL1
Locus ID 4016
Components

KN209830G1, LOXL1 gRNA vector 1 in pCas-Guide CRISPR vector

KN209830G2, LOXL1 gRNA vector 2 in pCas-Guide CRISPR vector

KN209830LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_005576
UniProt ID Q08397
Synonyms LOL; LOXL
Summary This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA102723 LOXL1 CRISPRa kit - CRISPR gene activation of human lysyl oxidase like 1 1 kit
$1,657.00
KN209830 LOXL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209830BN LOXL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209830RB LOXL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409830 LOXL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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