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TIMP2 Human Gene Knockout Kit (CRISPR)

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SKU
KN209796BN
TIMP2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "TIMP2 or AL713764"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol TIMP2
Locus ID 7077
Components

KN209796G1, TIMP2 gRNA vector 1 in pCas-Guide CRISPR vector

KN209796G2, TIMP2 gRNA vector 2 in pCas-Guide CRISPR vector

KN209796BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003255
UniProt ID P16035
Synonyms CSC-21K; DDC8
Summary This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA104880 TIMP2 CRISPRa kit - CRISPR gene activation of human TIMP metallopeptidase inhibitor 2 1 kit
$1,657.00
KN209796 TIMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209796LP TIMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209796RB TIMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409796 TIMP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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