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SOCS3 Human Gene Knockout Kit (CRISPR)

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SKU
KN209305BN
SOCS3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "SOCS3 or NM_003955"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol SOCS3
Locus ID 9021
Components

KN209305G1, SOCS3 gRNA vector 1 in pCas-Guide CRISPR vector

KN209305G2, SOCS3 gRNA vector 2 in pCas-Guide CRISPR vector

KN209305BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003955
UniProt ID O14543
Synonyms ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Summary This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
GA105994 SOCS3 CRISPRa kit - CRISPR gene activation of human suppressor of cytokine signaling 3 1 kit
$1,657.00
KN209305 SOCS3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209305LP SOCS3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209305RB SOCS3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409305 SOCS3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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