c Maf (MAF) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
|---|---|
| Vector | RFP-BSD |
| Target Symbol | c Maf |
| Locus ID | 4094 |
| Components |
KN209247G1, c Maf gRNA vector 1 in pCas-Guide CRISPR vector KN209247G2, c Maf gRNA vector 2 in pCas-Guide CRISPR vector KN209247RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001031804, NM_005360 |
| UniProt ID | O75444 |
| Synonyms | c-MAF; CCA4; CTRCT21 |
| Summary | The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2010 |
| Shipping | Ambient |
Reviews
Documents
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Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA102782 | MAF CRISPRa kit - CRISPR gene activation of human MAF bZIP transcription factor | 1 kit |
$1,657.00
|
|
| KN209247 | MAF - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN209247BN | MAF - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN209247LP | MAF - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN409247 | MAF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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