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ZNF281 Human Gene Knockout Kit (CRISPR)

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SKU
KN209243BN
ZNF281 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ZNF281 or NM_001281293"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol ZNF281
Locus ID 23528
Components

KN209243G1, ZNF281 gRNA vector 1 in pCas-Guide CRISPR vector

KN209243G2, ZNF281 gRNA vector 2 in pCas-Guide CRISPR vector

KN209243BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001281293, NM_001281294, NM_012482
UniProt ID Q9Y2X9
Synonyms ZBP-99; ZNP-99
Summary Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
GA108371 ZNF281 CRISPRa kit - CRISPR gene activation of human zinc finger protein 281 1 kit
$1,657.00
KN209243 ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209243LP ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209243RB ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409243 ZNF281 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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