Human ZNF281 activation kit by CRISPRa

SKU
GA108371
ZNF281 CRISPRa kit - CRISPR gene activation of human zinc finger protein 281
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZNF281
Locus ID 23528
Components

GA108371G1, ZNF281 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108371G2, ZNF281 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108371G3, ZNF281 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001281293, NM_001281294, NM_012482
UniProt ID Q9Y2X9
Synonyms ZBP-99; ZNP-99
Summary Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN209243 ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN209243BN ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209243LP ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN209243RB ZNF281 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409243 ZNF281 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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