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KIF17 Human Gene Knockout Kit (CRISPR)

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SKU
KN209079
KIF17 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol KIF17
Locus ID 57576
Components

KN209079G1, KIF17 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: GACAACCTTCACCGCCTCGG

KN209079G2, KIF17 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: TCTCGCTCCCGCTGGTTCAT

KN209079D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

AAGGCAGCGG ACGCGAAAGG AGCCCAGCCA GGGCTGGCGC TTCCCGCAAG CGGCCGCGCG TGGCTGCGGG GATCACTCGG GCGAAGCTCG CGGGCCAGGC GGGGCGTTCC CGGGGCCGCT CTTGTGACGC CACGGGCGTT GCCCAGCAAC CGCGAACGCC GCGGCGGTGA GCTTGCGGGC AGGCGGCTGG GGCGGCTCCG GGCTCGGGTT CTGCGGCGGC GCCTGCAGCG CGGATCCCCC ACGTCCCCGC TCGGGCCGGG CCTCAGAAAC GGGCGAGCCC GGGCGCGGGA GGAAGCGGCG GCCCCGGCTC GGGTCCTGCG ACGCCCAGCT CCCCTCCGGG GCGCCCCCCG AGGGGTCCCC GCCCCCCGCC GCGGCCCCGC CCCTGCCTCA AGGCCCCGCC CCCCGTGGCC GGCGCTGGCC CCGCCCCTTG GCCCGGGCTG CTGGGAGTCC CCGGCGGGGC GGGGGTCAGC TCTGGTCCCG TTGGTCCTGG GCGCGGCGCC GCTGCGCTGC CAGCCCGTGG TGACTGTGGA CTGCGCGCGC GCCCAGTGCT GCATCCAGAA CCCGGGCGCC GCCGACGAGC CGCCCAAGCA GTTCACCTTC GACGGCGCCT ACCACGTGGA CCACGTCACC GAGCAGATCT ACAACGAGAT CGCCTATCCG CTGGTGGAGG TGAGGGCGCC CGGCAGGCCG CCCTGCAGGC GGCAGGGCAT GAGGCCGCCC CGAGAGTCCC CAGGGGGCTG CGCTGCCCCC CAGCCAGGAG GAAAGGCCCT CGAGGGGCGC AGGCGGACGG GAACAGGTAG GTCCGGAGGC TTTTGTCCAG GCGGGACACA ACCAGAGCCT GCCTCTAATG TCGCCTCCGG GTCTGCACTA TCCCCAGCGT CTCCGCCTCC CGGGTTCAAG CGATTCTCCT GCCTCAGCCT CCCAAGTAGC TGGGATTACA GGTGCCTGCC ACCACGCCCG TCTAATTTTT GTGTTTTTAG TACAGATGGG GTTTCACCAT

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001122819, NM_001287212, NM_020816
UniProt ID Q9P2E2
Synonyms KIF3X; KIF17B; KLP-2; OSM-3
Summary Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA111603 KIF17 CRISPRa kit - CRISPR gene activation of human kinesin family member 17 1 kit
$1,657.00
KN209079BN KIF17 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209079LP KIF17 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209079RB KIF17 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409079 KIF17 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

Modulation of estrogen related receptor alpha activity by the kinesin KIF17
Seneviratne, Turan, Hermant et al
Oncotarget (2017) 8 (31), 50359-50375 DOI: 10.18632/oncotarget.18104
Cited by 8
FigureFigureFigure
Modulation of estrogen related receptor alpha activity by the kinesin KIF17
Seneviratne, Turan, Hermant et al
Oncotarget (2017) 8 (31), 50359-50375 DOI: 10.18632/oncotarget.18104
Snippet: … Genome-edited, KIF17 knock-out T84 cells were generated by transfecting plasmids designed for genome-wide, Cas9-mediated knock-out of human KIF17 (KN209079, OriGene). …KIF17 knock-out wa;;LM2NR cells were generated by transfecting LM2 cells with GFP-KIF17-TNR followed by sorting using the FACSAria II cell sorter (BD Biosciences). … Genome-edited, KIF17 knockout T84 cells were generated by transfecting plasmids designed for genome-wide, Cas9-mediated knock-out of human KIF17 (KN209079, OriGene)
Showing 1-2 of 2 papers.
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