ADCY6 Human Gene Knockout Kit (CRISPR)

SKU
KN209021BN
ADCY6 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol ADCY6
Locus ID 112
Components

KN209021G1, ADCY6 gRNA vector 1 in pCas-Guide CRISPR vector

KN209021G2, ADCY6 gRNA vector 2 in pCas-Guide CRISPR vector

KN209021BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_015270, NM_020983
UniProt ID O43306
Synonyms AC6; LCCS8
Summary This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. provided by RefSeq, May 2015
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Other Versions
SKU Description Size Price
GA100074 ADCY6 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 6 1 kit
$1,657.00
KN209021 ADCY6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209021LP ADCY6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN209021RB ADCY6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN409021 ADCY6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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