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beta Catenin (CTNNB1) Human Gene Knockout Kit (CRISPR)

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SKU
KN208947LP
CTNNB1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "beta Catenin or NM_001098209"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol beta Catenin
Locus ID 1499
Components

KN208947G1, beta Catenin gRNA vector 1 in pCas-Guide CRISPR vector

KN208947G2, beta Catenin gRNA vector 2 in pCas-Guide CRISPR vector

KN208947LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001098209, NM_001098210, NM_001904, NM_001330729
UniProt ID P35222
Synonyms armadillo; CTNNB; MRD19
Summary The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2016
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Other Versions
SKU Description Size Price
GA101060 CTNNB1 CRISPRa kit - CRISPR gene activation of human catenin beta 1 1 kit
$1,657.00
KN208947 CTNNB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208947BN CTNNB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208947RB CTNNB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408947 CTNNB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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