ARRDC3 Human Gene Knockout Kit (CRISPR)

CAT#: KN208809RB

ARRDC3 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: ARRDC3
• Locus ID: 57561
• Components:

  KN208809G1, ARRDC3 gRNA vector 1 in pCas-Guide CRISPR vector

  KN208809G2, ARRDC3 gRNA vector 2 in pCas-Guide CRISPR vector

  KN208809RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001329670, NM_001329671, NM_001329672, NM_020801, NR_138071, NR_138072
• UniProt ID: Q96B67
• Synonyms: TLIMP
• Summary: This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016]