RAC1 Human Gene Knockout Kit (CRISPR)

SKU KN208711BN

RAC1 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: RAC1
• Locus ID: 5879
• Components:

  KN208711G1, RAC1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN208711G2, RAC1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN208711BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_006908, NM_018890, NM_198829
• UniProt ID: P63000
• Synonyms: MIG5; p21-Rac1; Rac-1; TC-25
• Summary: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
• Shipping: Ambient