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FAM20B Human Gene Knockout Kit (CRISPR)

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SKU
KN208513BN
FAM20B - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "FAM20B or NM_014864"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol FAM20B
Locus ID 9917
Components

KN208513G1, FAM20B gRNA vector 1 in pCas-Guide CRISPR vector

KN208513G2, FAM20B gRNA vector 2 in pCas-Guide CRISPR vector

KN208513BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_014864, NM_001324310, NM_001324311
UniProt ID O75063
Synonyms gxk1
Summary Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA106702 FAM20B CRISPRa kit - CRISPR gene activation of human FAM20B glycosaminoglycan xylosylkinase 1 kit
$1,657.00
KN208513 FAM20B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208513LP FAM20B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208513RB FAM20B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408513 FAM20B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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