OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

ERO1LB (ERO1B) Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN208445
ERO1B - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC208445 ERO1LB (Myc-DDK-tagged)-Human ERO1-like beta (S. cerevisiae) (ERO1LB)
10 ug
$457.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "ERO1LB or AK001865"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol ERO1LB
Locus ID 56605
Components

KN208445G1, ERO1LB gRNA vector 1 in pCas-Guide CRISPR vector

KN208445G2, ERO1LB gRNA vector 2 in pCas-Guide CRISPR vector

KN208445D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_019891
UniProt ID Q86YB8
Synonyms DKFZp779C1042; DKFZp779I0141; FLJ11003
Summary Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.UniProtKB/Swiss-Prot Function
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA111197 ERO1B CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum oxidoreductase 1 beta 1 kit
$1,657.00
KN208445BN ERO1LB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208445LP ERO1LB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208445RB ERO1LB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408445 ERO1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products