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p63 (TP63) Human Gene Knockout Kit (CRISPR)

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SKU
KN208013RB
TP63 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "p63 or NM_001114978"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol p63
Locus ID 8626
Components

KN208013G1, p63 gRNA vector 1 in pCas-Guide CRISPR vector

KN208013G2, p63 gRNA vector 2 in pCas-Guide CRISPR vector

KN208013RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001114978, NM_001114979, NM_001114980, NM_001114981, NM_001114982, NM_001329144, NM_001329145, NM_001329146, NM_001329148, NM_001329149, NM_001329150, NM_001329964, NM_003722
UniProt ID Q9H3D4
Synonyms AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4
Summary This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. provided by RefSeq, Aug 2016
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Documents
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Other Versions
SKU Description Size Price
GA105712 TP63 CRISPRa kit - CRISPR gene activation of human tumor protein p63 1 kit
$1,657.00
KN208013 TP63 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208013BN TP63 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208013LP TP63 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408013 TP63 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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