RNF149 Human Gene Knockout Kit (CRISPR)

CAT#: KN207979RB

RNF149 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: RNF149
• Locus ID: 284996
• Components:

  KN207979G1, RNF149 gRNA vector 1 in pCas-Guide CRISPR vector

  KN207979G2, RNF149 gRNA vector 2 in pCas-Guide CRISPR vector

  KN207979RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_173647
• UniProt ID: Q8NC42
• Synonyms: DNAPTP2
• Summary: E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.[UniProtKB/Swiss-Prot Function]