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PTP epsilon (PTPRE) Human Gene Knockout Kit (CRISPR)

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SKU
KN207950LP
PTPRE - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PTP epsilon or AK056111"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol PTP epsilon
Locus ID 5791
Components

KN207950G1, PTP epsilon gRNA vector 1 in pCas-Guide CRISPR vector

KN207950G2, PTP epsilon gRNA vector 2 in pCas-Guide CRISPR vector

KN207950LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001316676, NM_001316677, NM_006504, NM_130435, NM_001323354, NM_001323355, NM_001323356, NM_001323357
UniProt ID P23469
Synonyms HPTPE; PTPE; R-PTP-EPSILON
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. provided by RefSeq, Oct 2015
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Documents
Resources
Other Versions
SKU Description Size Price
GA103935 PTPRE CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type E 1 kit
$1,657.00
KN207950 PTPRE - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207950BN PTPRE - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207950RB PTPRE - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407950 PTPRE - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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