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LILRB2 Human Gene Knockout Kit (CRISPR)

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SKU
KN207770LP
LILRB2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "LILRB2 or NM_001080978"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol LILRB2
Locus ID 10288
Components

KN207770G1, LILRB2 gRNA vector 1 in pCas-Guide CRISPR vector

KN207770G2, LILRB2 gRNA vector 2 in pCas-Guide CRISPR vector

KN207770LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001080978, NM_001278403, NM_001278404, NM_001278405, NM_001278406, NM_005874, NR_103521
Synonyms CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
Summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA107009 LILRB2 CRISPRa kit - CRISPR gene activation of human leukocyte immunoglobulin like receptor B2 1 kit
$1,657.00
KN207770 LILRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207770BN LILRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207770RB LILRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407770 LILRB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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