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PARN Human Gene Knockout Kit (CRISPR)

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SKU
KN207220BN
PARN - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PARN or NM_001134477"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PARN
Locus ID 5073
Components

KN207220G1, PARN gRNA vector 1 in pCas-Guide CRISPR vector

KN207220G2, PARN gRNA vector 2 in pCas-Guide CRISPR vector

KN207220BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001134477, NM_001242992, NM_002582
UniProt ID O95453
Synonyms DAN; DKCB6; PFBMFT4
Summary The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA103387 PARN CRISPRa kit - CRISPR gene activation of human poly(A)-specific ribonuclease 1 kit
$1,657.00
KN207220 PARN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207220LP PARN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207220RB PARN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407220 PARN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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