CISD2 Human Gene Knockout Kit (CRISPR)

CAT#: KN207131RB

CISD2 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: CISD2
• Locus ID: 493856
• Components:

  KN207131G1, CISD2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN207131G2, CISD2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN207131RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001008388
• UniProt ID: Q8N5K1
• Synonyms: ERIS; Miner1; NAF-1; WFS2; ZCD2
• Summary: The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]