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NALP12 (NLRP12) Human Gene Knockout Kit (CRISPR)

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SKU
KN207045BN
NLRP12 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "NALP12 or NM_001277126"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol NALP12
Locus ID 91662
Components

KN207045G1, NALP12 gRNA vector 1 in pCas-Guide CRISPR vector

KN207045G2, NALP12 gRNA vector 2 in pCas-Guide CRISPR vector

KN207045BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001277126, NM_001277129, NM_033297, NM_144687
UniProt ID P59046
Synonyms CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
Summary This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2013
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Documents
Resources
Other Versions
SKU Description Size Price
GA114138 NLRP12 CRISPRa kit - CRISPR gene activation of human NLR family pyrin domain containing 12 1 kit
$1,657.00
KN207045 NLRP12 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207045LP NLRP12 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207045RB NLRP12 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407045 NLRP12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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