Activin A Receptor Type IB (ACVR1B) Human Gene Knockout Kit (CRISPR)

SKU
KN206920LP
ACVR1B - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Activin A Receptor Type IB
Locus ID 91
Components

KN206920G1, Activin A Receptor Type IB gRNA vector 1 in pCas-Guide CRISPR vector

KN206920G2, Activin A Receptor Type IB gRNA vector 2 in pCas-Guide CRISPR vector

KN206920LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004302, NM_020327, NM_020328
UniProt ID P36896
Synonyms ACTRIB; ACVRLK4; ALK4; SKR2
Summary This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.provided by RefSeq, Jun 2010
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Other Versions
SKU Description Size Price
GA100057 ACVR1B CRISPRa kit - CRISPR gene activation of human activin A receptor type 1B 1 kit
$1,657.00
KN206920 ACVR1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206920BN ACVR1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206920RB ACVR1B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406920 ACVR1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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