CD2 Human Gene Knockout Kit (CRISPR)

SKU KN206612LP

CD2 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: CD2
• Locus ID: 914
• Components:

  KN206612G1, CD2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN206612G2, CD2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN206612LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001328609, NM_001767
• UniProt ID: P06729
• Synonyms: LFA-2; SRBC; T11
• Summary: The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
• Shipping: Ambient