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SIAH1 Human Gene Knockout Kit (CRISPR)

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SKU
KN206576RB
SIAH1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC206576 SIAH1 (Myc-DDK-tagged)-Human seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1
10 ug
$450.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "SIAH1 or AK094663"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol SIAH1
Locus ID 6477
Components

KN206576G1, SIAH1 gRNA vector 1 in pCas-Guide CRISPR vector

KN206576G2, SIAH1 gRNA vector 2 in pCas-Guide CRISPR vector

KN206576RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001006610, NM_001006611, NM_003031
UniProt ID Q8IUQ4
Synonyms SIAH1A
Summary This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
GA104408 SIAH1 CRISPRa kit - CRISPR gene activation of human siah E3 ubiquitin protein ligase 1 1 kit
$1,657.00
KN206576 SIAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206576BN SIAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206576LP SIAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406576 SIAH1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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