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RBM7 Human Gene Knockout Kit (CRISPR)

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SKU
KN206461
RBM7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol RBM7
Locus ID 10179
Components

KN206461G1, RBM7 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: CCTTGAAACGAAAGTGACCG

KN206461G2, RBM7 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: AAGCTCGAAAAGGAGCTCCT

KN206461D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

GCTTGGCGGC TCCGGCCCCG GCCATCTGGT TCCCTTGGGC TCCGGCCGCC ACCATCCACT CGACGGCTCT CGGCCCGAAC GCTTGGTCGC ACCGCCTGCC GAGGTCCTAG ATGAATCGCT TCAGGCCTGG AAACGAGGAA GCCGTCTCCG GAGACCATCG CCAACGCTGA CGCCCGCGGT CTGAGGTCGC CATGGGAAGA GCGGTAGGCC ACCCTGCTCC TCTGATCACC GGAGGACAGG GACACATTGT TCAGGGCCAT ATTCAAACAC TGCCCGCAGT ACTTGCGTTA CGTCCCTTTG TGAAGGCAGG CCCTTCGCGG CTCCCCAGAT CAGTCCAGCC TGTGTCGGAC CCGATGACTA AGCACACAGG AACCCATAAC TGAGCCTGCG GAAGAGCCAG AAGCCGCCTT GCCTTTAACG AGGGGTATCC TGGCGAGCAT GCGCAGACCG TCCGCGCACG TCGTCGCCCG CTGAGAGCAA GCGCAACGGG CGTTTTCGTT TGTGACGCCA GGGAGCGTGA GGACGTGGGG CTTCCGTGAA TGCGCAGTGG GTGCGTCGGC CACGACCTTT TGGCCAGGTT AGGGAGGGGG CGACGCTGAG GCTGGGTTCG GCCCTTTGCC TTTCGTTTTC CGTCTCGCCT AGGGCCTGGC CAGCGGCCAC CCCGTTTTCT TTTCGTAGCC GTCAGGGGAC CCGACGGGTG GCTGTTTGGG GGTGAAAGGC GGGTCTGGGT TGCGAAACGC TCGCTGGGTG TCGCTTTCCT GGAAGATCTT GGTTCGTTTA GGCCGAAAGT GACGACTAAA GGTGGTGGAG GGATCCTCGA TCAGGTTTCC CGTGGTAGAG ATCCAGGGGT CCTTGGGAAC ACAGTGTGTG TGTAGGGTCT TCGTTGAGCA GTGCTTTTTC TTATCCTTCC TGTTGTCATC TTCCCCTTAG GATAATTTGT CTTTGGTTTA TCTGACTGGG AACTTAATAT TTTAATTTAT TTGTGTCTGT TTTCCCCTAA AGTTTGCTTA TCAAATTGCA GCATTATTAA AATATGTAAA ATAAAATGGT TAAGTACTCC GTAGAAAAAC AGCATTTTAG TGTTGCTGTA TTAAAAAGTG TGAAAAATTC TGAGTATCCT ATTCCCCCCA TCCCTATCCC CTAATAACTG GTATTGTTTG ATTAATCAAT ACAAAAGTCC GTTTTTAGTT AAAGAAAATC

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001286045, NM_001286046, NM_001286047, NM_001286048, NM_016090
UniProt ID Q9Y580
Summary Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). Possible involved in germ cell RNA processing and meiosis (Probable).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA106915 RBM7 CRISPRa kit - CRISPR gene activation of human RNA binding motif protein 7 1 kit
$1,657.00
KN206461BN RBM7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206461LP RBM7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206461RB RBM7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406461 RBM7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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