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CD4 Human Gene Knockout Kit (CRISPR)

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SKU
KN206453RB
CD4 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CD4 or NM_000616"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol CD4
Locus ID 920
Components

KN206453G1, CD4 gRNA vector 1 in pCas-Guide CRISPR vector

KN206453G2, CD4 gRNA vector 2 in pCas-Guide CRISPR vector

KN206453RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000616, NM_001195014, NM_001195015, NM_001195016, NM_001195017, NR_036545
UniProt ID P01730
Synonyms CD4mut
Summary This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. provided by RefSeq, May 2020
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Other Versions
SKU Description Size Price
GA100647 CD4 CRISPRa kit - CRISPR gene activation of human CD4 molecule 1 kit
$1,657.00
KN206453 CD4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206453BN CD4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206453LP CD4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406453 CD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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