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PTGS1 Human Gene Knockout Kit (CRISPR)

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SKU
KN206436BN
PTGS1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PTGS1 or NM_000962"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PTGS1
Locus ID 5742
Components

KN206436G1, PTGS1 gRNA vector 1 in pCas-Guide CRISPR vector

KN206436G2, PTGS1 gRNA vector 2 in pCas-Guide CRISPR vector

KN206436BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000962, NM_001271164, NM_001271165, NM_001271166, NM_001271367, NM_001271368, NM_080591
UniProt ID P23219
Synonyms COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS
Summary This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2014
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Other Versions
SKU Description Size Price
GA103906 PTGS1 CRISPRa kit - CRISPR gene activation of human prostaglandin-endoperoxide synthase 1 1 kit
$1,657.00
KN206436 PTGS1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206436LP PTGS1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206436RB PTGS1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406436 PTGS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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