AMBRA1 Human Gene Knockout Kit (CRISPR)

CAT#: KN206255LP

AMBRA1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: AMBRA1
• Locus ID: 55626
• Components:

  KN206255G1, AMBRA1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN206255G2, AMBRA1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN206255LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001267782, NM_001267783, NM_001300731, NM_017749, NM_001367468, NM_001367470, NM_001367471, NM_001367469, NR_160027
• UniProt ID: Q9C0C7
• Synonyms: DCAF3; WDR94
• Summary: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity).[UniProtKB/Swiss-Prot Function]