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Glypican 3 (GPC3) Human Gene Knockout Kit (CRISPR)

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SKU
KN205911LP
GPC3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Glypican 3 or NM_001164617"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Glypican 3
Locus ID 2719
Components

KN205911G1, Glypican 3 gRNA vector 1 in pCas-Guide CRISPR vector

KN205911G2, Glypican 3 gRNA vector 2 in pCas-Guide CRISPR vector

KN205911LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001164617, NM_001164618, NM_001164619, NM_004484
UniProt ID P51654
Synonyms DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1
Summary Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
GA101815 GPC3 CRISPRa kit - CRISPR gene activation of human glypican 3 1 kit
$1,657.00
KN205911 GPC3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205911BN GPC3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205911RB GPC3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405911 GPC3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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