HHLA2 Human Gene Knockout Kit (CRISPR)

CAT#: KN205909RB

HHLA2 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: HHLA2
• Locus ID: 11148
• Components:

  KN205909G1, HHLA2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN205909G2, HHLA2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN205909RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001282556, NM_001282557, NM_001282558, NM_001282559, NM_007072, NM_001370244
• UniProt ID: Q9UM44
• Synonyms: B7-H7; B7H7
• Summary: This gene encodes a protein ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]