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Aromatase (CYP19A1) Human Gene Knockout Kit (CRISPR)

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SKU
KN205890RB
CYP19A1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Aromatase or NM_000103"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Aromatase
Locus ID 1588
Components

KN205890G1, Aromatase gRNA vector 1 in pCas-Guide CRISPR vector

KN205890G2, Aromatase gRNA vector 2 in pCas-Guide CRISPR vector

KN205890RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000103, NM_031226, NM_001347248, NM_001347249, NM_001347250, NM_001347251, NM_001347252, NM_001347253, NM_001347254, NM_001347255, NM_001347256
UniProt ID P11511
Synonyms ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. provided by RefSeq, Dec 2016
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Other Versions
SKU Description Size Price
GA101117 CYP19A1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 19 subfamily A member 1 1 kit
$1,657.00
KN205890 CYP19A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205890BN CYP19A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205890LP CYP19A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405890 CYP19A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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