EIF4A2 Human Gene Knockout Kit (CRISPR)

SKU
KN205623BN
EIF4A2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol EIF4A2
Locus ID 1974
Components

KN205623G1, EIF4A2 gRNA vector 1 in pCas-Guide CRISPR vector

KN205623G2, EIF4A2 gRNA vector 2 in pCas-Guide CRISPR vector

KN205623BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001967
UniProt ID Q14240
Synonyms BM-010; DDX2B; eIF-4A-II; EIF4A; eIF4A-II; EIF4F
Summary ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA101367 EIF4A2 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 4A2 1 kit
$1,657.00
KN205623 EIF4A2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205623LP EIF4A2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205623RB EIF4A2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405623 EIF4A2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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