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SHCBP1 Human Gene Knockout Kit (CRISPR)

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SKU
KN205527
SHCBP1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol SHCBP1
Locus ID 79801
Components

KN205527G1, SHCBP1 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: GGAAATTTGAAATGGCTGAC

KN205527G2, SHCBP1 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: ATGGCTGACGGGTCGCTGAC

KN205527D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

TGTTAGCCAT TATGATGGAG ATTATAGTTG TCTTTGATTA ATGCAAATTA ACAAATTTAC TTACTAAATT TAATTTGACA TTCTTTGAAA ATATGCTCTC TCTCTCTCTC TCTCTCTCTG TGTGTGTGTG TGTGTGTGTG TGTGTATTGA AAGACAGAGA GAGACTGGTG TTTGGTGGTG AAAGTTTTGG GCCCACGTAG GCCAGCATCC TTTTCAGTTG AAGTTGTGCT TGTGGGAGGT GAAATGACTT GCCCAAGGCA ATACCACTAG GAATAGCCCA GGTAAGTTTA AATACTATGT TTTTTGACTC TCAACCCAGT GACTTTTCCA CTATATCTCA TTTCCAGGCA TTGCTGGTTC GTTTTTTTCG AAAATCATTC CAAATTATAT TCCAATTCGA CTTTCTTCAA GTTCATCCCA GAAAAGCAAA GGCCGGGCAC TTGAACAAGA ACAGCTGTCA GCCTGGGGCG AGGGGGCAGT GTTGGTGGGG GCTGGAGCGG GGCCGGACTC TAATTGGTCC ACGGCCTCGG CCCGACTATC AAATCAGCAG AGCCTGCGTC ATCACGTCGT TGCCTGGGCT GCCGTCCGCG GAAATTTGAA GGCGCCGGAG CGCATGGGCT GGGCGGTGGA GCAGGAGCTG GCGTCTCTGG AGAAAGGTGA GCTCTCCATG CCGGGGCCGA GGAGCCGCCT CTGAGCGGAG GCCTGGGGCG TCGGGACCCT AGGAGGGCGC CTGGGTCGCG GGCCTTCCGG ACCCGTCTGT CCAGGGTGGC GGGAACGGCG GTGCGCGGCC GGGACCCAGT GACGGGACCT CAAAGTCGGG CGGTACCCAG GGGTGGGGGA CTCCCTCTCT TCCCTATCCG CATCTCCCAC TCTCCCTGCA CTCTCTGGCC TCCGCCCGCC CCGAGGTTGG AGGGAGCTGG ATTGGGCCAG GAATTCCCTA TCTGGATGGG TTTTGCGGGA ACTGTGCATT TACTGTTGCT CAAGGGGCCA TTTTTTCATC TGCATCTCAA AGGAGATCAC GAACCACACT TCCCTTTTCC GAAGAAGAGA AAAGCTTGAA CCCTTGGCTT AGATGGCTGT CCTGTGCACG GAGGGTAGTG ACGTGTCCAA AGTGAGGAGC GCCAACTTGG GCCGGAGTCC AGAAATAGAA CCGGGGTCTT CTAGTTCTCT GCCCTTTCTT CCTCCTCATA GAGTTTCATT

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001324318, NM_001324319, NM_024745, NR_136738
UniProt ID Q8NEM2
Synonyms PAL
Summary May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA112636 SHCBP1 CRISPRa kit - CRISPR gene activation of human SHC binding and spindle associated 1 1 kit
$1,657.00
KN205527BN SHCBP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205527LP SHCBP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205527RB SHCBP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405527 SHCBP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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