OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

GIRK1 (KCNJ3) Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN205322RB
KCNJ3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA504152 KCNJ3 (GIRK1 ) mouse monoclonal antibody, clone OTI3E11 (formerly 3E11) 100 ul
$447.00
RC205322 KCNJ3 (Myc-DDK-tagged)-Human potassium inwardly-rectifying channel, subfamily J, member 3 (KCNJ3)
10 ug
$466.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "GIRK1 or NM_001260508"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol GIRK1
Locus ID 3760
Components

KN205322G1, GIRK1 gRNA vector 1 in pCas-Guide CRISPR vector

KN205322G2, GIRK1 gRNA vector 2 in pCas-Guide CRISPR vector

KN205322RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001260508, NM_001260509, NM_001260510, NM_002239
UniProt ID P48549
Synonyms GIRK1; KGA; KIR3.1
Summary Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. provided by RefSeq, May 2012
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA102536 KCNJ3 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 3 1 kit
$1,657.00
KN205322 KCNJ3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205322BN KCNJ3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205322LP KCNJ3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405322 KCNJ3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products