GNG4 Human Gene Knockout Kit (CRISPR)

SKU KN205299LP

GNG4 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: GNG4
• Locus ID: 2786
• Components:

  KN205299G1, GNG4 gRNA vector 1 in pCas-Guide CRISPR vector

  KN205299G2, GNG4 gRNA vector 2 in pCas-Guide CRISPR vector

  KN205299LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001098721, NM_001098722, NM_004485
• UniProt ID: P50150
• Synonyms: DKFZp547K1018; FLJ23803; FLJ34187
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[UniProtKB/Swiss-Prot Function]
• Shipping: Ambient