GPRC5B Human Gene Knockout Kit (CRISPR)

CAT#: KN205201LP

GPRC5B - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: GPRC5B
• Locus ID: 51704
• Components:

  KN205201G1, GPRC5B gRNA vector 1 in pCas-Guide CRISPR vector

  KN205201G2, GPRC5B gRNA vector 2 in pCas-Guide CRISPR vector

  KN205201LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001304771, NM_016235
• UniProt ID: Q9NZH0
• Synonyms: RAIG-2; RAIG2
• Summary: This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]