Carbonic Anhydrase IX (CA9) Human Gene Knockout Kit (CRISPR)

SKU
KN204839LP
CA9 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Carbonic Anhydrase IX
Locus ID 768
Components

KN204839G1, Carbonic Anhydrase IX gRNA vector 1 in pCas-Guide CRISPR vector

KN204839G2, Carbonic Anhydrase IX gRNA vector 2 in pCas-Guide CRISPR vector

KN204839LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001216
UniProt ID Q16790
Synonyms CAIX; MN
Summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. provided by RefSeq, Jun 2014
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Other Versions
SKU Description Size Price
GA100535 CA9 CRISPRa kit - CRISPR gene activation of human carbonic anhydrase 9 1 kit
$1,657.00
KN204839 CA9 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204839BN CA9 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204839RB CA9 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404839 CA9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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