MIRO2 (RHOT2) Human Gene Knockout Kit (CRISPR)

SKU KN204823LP

RHOT2 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: MIRO2
• Locus ID: 89941
• Components:

  KN204823G1, MIRO2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN204823G2, MIRO2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN204823LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_138769, NM_001352275, NM_001352276, NM_001352277, NM_001352278, NM_001352279, NM_001352280, NM_001352281, NM_001352282, NM_001352283, NM_001352284, NM_001352285, NM_001352286, NM_001352287, NM_001352288, NM_001352289, NM_001352290, NM_001352291, NM_001352292, NM_001352293, NM_001352294, NR_147953, NR_147954, NR_147955, NR_147956
• UniProt ID: Q8IXI1
• Synonyms: ARHT2; C16orf39; MIRO-2; MIRO2; RASL
• Summary: This gene encodes a member of the Rho family of GTPases. The encoded protein is localized to the outer mitochondrial membrane and plays a role in mitochondrial trafficking and fusion-fission dynamics. [provided by RefSeq, Nov 2011]
• Shipping: Ambient