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TAX1BP3 Human Gene Knockout Kit (CRISPR)

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SKU
KN204776LP
TAX1BP3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "TAX1BP3 or NM_001204698"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol TAX1BP3
Locus ID 30851
Components

KN204776G1, TAX1BP3 gRNA vector 1 in pCas-Guide CRISPR vector

KN204776G2, TAX1BP3 gRNA vector 2 in pCas-Guide CRISPR vector

KN204776LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001204698, NM_014604
UniProt ID O14907
Synonyms TIP-1
Summary This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Apr 2017
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Documents
Resources
Other Versions
SKU Description Size Price
GA109404 TAX1BP3 CRISPRa kit - CRISPR gene activation of human Tax1 binding protein 3 1 kit
$1,657.00
KN204776 TAX1BP3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204776BN TAX1BP3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204776RB TAX1BP3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404776 TAX1BP3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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