RAGE (AGER) Human Gene Knockout Kit (CRISPR)

SKU
KN204664BN
AGER - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol RAGE
Locus ID 177
Components

KN204664G1, RAGE gRNA vector 1 in pCas-Guide CRISPR vector

KN204664G2, RAGE gRNA vector 2 in pCas-Guide CRISPR vector

KN204664BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001136, NM_001206929, NM_001206932, NM_001206934, NM_001206936, NM_001206940, NM_001206954, NM_001206966, NM_172197, NR_038190
UniProt ID Q15109
Synonyms RAGE
Summary The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). provided by RefSeq, May 2011
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Other Versions
SKU Description Size Price
GA100125 AGER CRISPRa kit - CRISPR gene activation of human advanced glycosylation end-product specific receptor 1 kit
$1,657.00
KN204664 AGER - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204664LP AGER - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204664RB AGER - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404664 AGER - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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