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DDX3 (DDX3X) Human Gene Knockout Kit (CRISPR)

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SKU
KN204171LP
DDX3X - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "DDX3 or NM_001193416"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol DDX3
Locus ID 1654
Components

KN204171G1, DDX3 gRNA vector 1 in pCas-Guide CRISPR vector

KN204171G2, DDX3 gRNA vector 2 in pCas-Guide CRISPR vector

KN204171LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001193416, NM_001193417, NM_001356, NM_024005, NR_126093, NR_126094, NM_001363819
UniProt ID O00571
Synonyms CAP-Rf; DBX; DDX3; DDX14; HLP2
Summary The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014
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Other Versions
SKU Description Size Price
GA101167 DDX3X CRISPRa kit - CRISPR gene activation of human DEAD-box helicase 3 X-linked 1 kit
$1,657.00
KN204171 DDX3X - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204171BN DDX3X - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204171RB DDX3X - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404171 DDX3X - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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