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TNFRSF1A Human Gene Knockout Kit (CRISPR)

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SKU
KN204008LP
TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC204008 TNFRSF1A (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "TNFRSF1A or NM_001065"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol TNFRSF1A
Locus ID 7132
Components

KN204008G1, TNFRSF1A gRNA vector 1 in pCas-Guide CRISPR vector

KN204008G2, TNFRSF1A gRNA vector 2 in pCas-Guide CRISPR vector

KN204008LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001065, NM_001346091, NM_001346092, NR_144351
UniProt ID P19438
Synonyms CD120a; FPF; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55
Summary This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA104924 TNFRSF1A CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 1A 1 kit
$1,657.00
KN204008 TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204008BN TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204008RB TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404008 TNFRSF1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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