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Human TNFRSF1A activation kit by CRISPRa

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SKU
GA104924
TNFRSF1A CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 1A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC204008 TNFRSF1A (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A)
10 ug
$457.00

Other products for "TNFRSF1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TNFRSF1A
Locus ID 7132
Components

GA104924G1, TNFRSF1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104924G2, TNFRSF1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104924G3, TNFRSF1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001065, NM_001346091, NM_001346092, NR_144351
UniProt ID P19438
Synonyms CD120a; FPF; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55
Summary This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN204008 TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204008BN TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204008LP TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204008RB TNFRSF1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404008 TNFRSF1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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