Calreticulin (CALR) Human Gene Knockout Kit (CRISPR)

SKU
KN203222LP
CALR - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Calreticulin
Locus ID 811
Components

KN203222G1, Calreticulin gRNA vector 1 in pCas-Guide CRISPR vector

KN203222G2, Calreticulin gRNA vector 2 in pCas-Guide CRISPR vector

KN203222LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004343
UniProt ID P27797
Synonyms cC1qR; CRT; HEL-S-99n; RO; SSA
Summary Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.provided by RefSeq, May 2020
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Documents
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Other Versions
SKU Description Size Price
GA100565 CALR CRISPRa kit - CRISPR gene activation of human calreticulin 1 kit
$1,657.00
KN203222 CALR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203222BN CALR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203222RB CALR - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403222 CALR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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