CD38 Human Gene Knockout Kit (CRISPR)

SKU
KN203179LP
CD38 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol CD38
Locus ID 952
Components

KN203179G1, CD38 gRNA vector 1 in pCas-Guide CRISPR vector

KN203179G2, CD38 gRNA vector 2 in pCas-Guide CRISPR vector

KN203179LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001775, NR_132660
UniProt ID P28907
Synonyms ADPRC 1; T10
Summary The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
GA100674 CD38 CRISPRa kit - CRISPR gene activation of human CD38 molecule 1 kit
$1,657.00
KN203179 CD38 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203179BN CD38 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203179RB CD38 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403179 CD38 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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