MEK5 (MAP2K5) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | MEK5 |
| Locus ID | 5607 |
| Components |
KN203171G1, MEK5 gRNA vector 1 in pCas-Guide CRISPR vector KN203171G2, MEK5 gRNA vector 2 in pCas-Guide CRISPR vector KN203171BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001206804, NM_002757, NM_145160, NM_145161, NM_145162 |
| UniProt ID | Q13163 |
| Synonyms | HsT17454; MAPKK5; MEK5; PRKMK5 |
| Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. provided by RefSeq, May 2011 |
| Shipping | Ambient |
Reviews
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Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA103797 | MAP2K5 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase 5 | 1 kit |
$1,657.00
|
|
| KN203171 | MAP2K5 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN203171LP | MAP2K5 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN203171RB | MAP2K5 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN403171 | MAP2K5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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