Serum Amyloid P (APCS) Human Gene Knockout Kit (CRISPR)

SKU
KN202802LP
APCS - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Serum Amyloid P
Locus ID 325
Components

KN202802G1, Serum Amyloid P gRNA vector 1 in pCas-Guide CRISPR vector

KN202802G2, Serum Amyloid P gRNA vector 2 in pCas-Guide CRISPR vector

KN202802LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001639
UniProt ID P02743
Synonyms HEL-S-92n; PTX2; SAP
Summary The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. provided by RefSeq, Sep 2008
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Other Versions
SKU Description Size Price
GA100226 APCS CRISPRa kit - CRISPR gene activation of human amyloid P component, serum 1 kit
$1,657.00
KN202802 APCS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202802BN APCS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202802RB APCS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402802 APCS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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