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Prostaglandin E Synthase (PTGES) Human Gene Knockout Kit (CRISPR)

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SKU
KN202405RB
PTGES - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC202405 PTGES (Myc-DDK-tagged)-Human prostaglandin E synthase (PTGES)
10 ug
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "Prostaglandin E Synthase or NM_004878"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Prostaglandin E Synthase
Locus ID 9536
Components

KN202405G1, Prostaglandin E Synthase gRNA vector 1 in pCas-Guide CRISPR vector

KN202405G2, Prostaglandin E Synthase gRNA vector 2 in pCas-Guide CRISPR vector

KN202405RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004878, NM_198797
UniProt ID O14684
Synonyms MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; PGES; PIG12; PP102; PP1294; TP53I12
Summary The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA106381 PTGES CRISPRa kit - CRISPR gene activation of human prostaglandin E synthase 1 kit
$1,657.00
KN202405 PTGES - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202405BN PTGES - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202405LP PTGES - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402405 PTGES - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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